JOHANNESBURG - UDM leader Bantu Holomisa says the ANC can't investigate itself.
President Cyril Ramaphosa has called for COVID-19 corruption claims to be probed.
The President appointed an Inter-Ministerial Committee to deal with alleged corruption in the PPE procurement processes.
"We cannot expect the ANC to investigate itself. These people are contaminated. The whole body is contaminated. Right now, we are not getting answers," he said.
Holomisa says the Cabinet needs to be dissolved and replaced by a caretaker administration.
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"The current executive, members of the government should resign with immediate effect, especially after they announced that they will set aside an amount of R500-billion to deal with the pandemic.
"Instead, what we are seeing now is the involvement of ANC leaders and their families in looting the same money earmarked to attend to the coronavirus pandemic."
South Africa's COVID-19 death toll has surpassed 11,000.