CAPE TOWN - Western Cape police are calling for assistance after the three men were shot dead in Mitchells Plain on Sunday night.
The men, aged 21, 22 and 36, are believed to have been returning home from a Rasta festival.
They came under fire on Bayern Munich Road in Tafelsig.
The bodies of two men were discovered on the scene, while a third victim died later at a healthcare facility.
Police say the motive is unknown, but are not ruling out the possibility that it is gang-related.
Anyone with information can contact Crime Stop on 08600 10111 or anonymously via the MySAPS mobile app.