Iyer is not part of India's T20 squad, which will play five matches in Australia that will serve as a tune-up for the T20 World Cup in India and Sri Lanka in February-March.
Sinner, looking to take advantage of rival Carlos Alcaraz's shock second-round loss to Cameron Norrie, extended his winning streak to 24 successive matches on indoor hard courts.
The Guinean took a touch and blasted through the outstretched hand of Augsburg goalkeeper Finn Dahmen. The goal was Guirassy's first in the league since mid-September.