Manchester United face Chelsea on Sunday with interim manager Ruud van Nistelrooy at the helm while faltering Arsenal face a potentially tricky trip to Newcastle.
Ruben Amorim says Manchester United told him it was "now or never" after being handed a brief midway through the season to restore the Premier League giants to the pinnacle of English and European football.
Who starts at fly-half and scrum-half will command most attention when world champions South Africa launch a three-Test tour of Britain on November 10 against Scotland in Edinburgh.
Ruben Amorim has promised to clarify his future after Sporting Lisbon's match on Friday as speculation mounts that he is on the brink of becoming Manchester United's new manager.